Neonatal Neuro Imaging
ADC Map (i) and R2 Map (ii) for an infant diagnosed with severe HI
ADC map (iii) and R2 map (iv) for an infant with mild HI
Apparent Diffusion Coefficient (ADC) map of an infant born prematurely and scanned at term age.
The apparent diffusion coefficient is a measure of the mobility of water molecules within tissue.
Cerebral Spinal Fluid (CSF) has a high ADC value because there are no restrictions to the motion
of the water molecules. In brain tissue the motion of water molecules is restricted by membranes,
macromolecules etc, which reduce ADC value.
Fractional Anisotropy (FA) map of same infant. FA is a measure of the directional dependence of
the motion of water molecules. Bright areas correspond to fibre tracts within the brain.
Colored FA (i) Colored FA (ii)
Colored FA (i) :- Colour Fractional Anisotropy (FA) map of same infant. The intensity of the image
is scaled by the FA map. The colours on the image correspond to the principle direction of the
water motion. Blue is motion in/out of the plane of the image, green is motion up/down and red
represents motion left/right. Colored FA (ii) :- Colour Fractional Anisotropy of same infant, from a slice higher in the brain.
ADC Map of whole volume
Multi-slice display of the ADC values of an infant born prematurely and scanned at term age.
MP-RAGE volumetric image of a pre-term infant. It can be noted that the contrast between the
white and gray matter is reversed compared to adult. Additionally, the degree of folding in the
brain is markedly reduced compared to the adult image. A research project was conducted for
preterm infant with a bleed in the brain. Brain volume differences between infants with and
without a bleed were investigated.
MP-RAGE volumetric image of a term aged infant.
MP-RAGE volumetric image of a young adult. 3D volumetric images can be used to quantify the volume of
brain tissue (white matter, gray matter). A research project at the 3.0T MRI scanner has quantified
white and gray matter tissue volume differences in children with Autism and Tourette Syndrome.